Extensive Use of Monosodium Glutamate - A Threat To Public Health
The term “Chinese restaurant syndrome” (CRS) was first used more than four decades ago. At the onset of symptoms patients experience complaints such as a burning sensation at the back of the neck, blistering on both arms and occasionally on the anterior thorax, general weakness, fatigue and palpitations. These symptoms occur 20 minutes after consumption of a meal rich in MSG (Bawaskar et al., 2017). Other symptoms that may appear later include flushing, dizziness, syncope and facial pressure. In a study that explored negative dietary effects of MSG, double blind and placebo-controlled trails were performed in which the administration of MSG, doses ranging from 57 to 150 mg/kg, was compared with the administration of a dose of 24 mg/kg NaCl. MSG as well as NaCl administration resulted in muscle pain and/or changes in mechanical sensitivity. MSG administration however was also associated with headache and tenderness of the pericranial muscles. Furthermore, administration of a high dose of more than 75 mg/kg MSG significantly elevated systolic blood pressure (Obayashi and Nagamura, 2016; Shimada et al., 2015). It is not well understood if MSG is correlated with complex cases of CRS (Kazmi et al., 2017).
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