Russ, I tried the dosage of Algin on the bottle and then your suggested use (4 3xs/day) and felt worse. I am also on DMSA (100 mg/1 day, 3 days off). Everytime I try to add a supplement i.e. chlorella, milk thistle, and now Algin, my symptoms get worse. Does this just mean I need to go slower? I had the last of my amalgams removed on 2/8 and felt great (like I hadn't felt in years) right afterwards. Then started the DMSA chelation on 2/16 and now am tired again and it only get worse if I add supplements (however, multi vit / minerals and Vit C don't bother me.) Thanks, Gabriella