Thanks for the response. My doctor would never prescribe it. I never feel fluey or shakey, infact i havnt actually had a cold or anything like that for years. I have been taking thyroxine for 12 yrs, i was never depressed, not until about 5mths ago when i got 3 teeth pulled out, i do have alot of the other symptoms like being cold, constipation etc. On the link you gave me there are only names of doctors, no adresses, i will go on the other websites and have a look. Do you take Armour with thyroxine? I see you can buy it online.