From the small amount of information I have on bile salts (also known as ox bile), it appears they help promote bile production and may have a "flushing" effect on the liver and gallbladder. I honestly don't know if bile salts would have the same effect for some people as milk thistle does.

Personally, before I had my amalgams removed, I couldn't take milk thistle because it aggravated my symptoms, especially the emotional ones like irritability and mood swings. I haven't tried taking it since my amalgams were removed, so I don't know what the effect would be now.

Interestingly, according to information I've researched about Traditional Chinese Medicine,

"Emotions are believed to be connected to the internal organs, with each internal organ being responsible for a specific emotion, and vice versa. For example, liver stagnation is said to cause feelings of anger, frustration, depression and moodiness. Liver function is also believed to regulate the smooth flow of qi, or chi (interpreted as "energy“) throughout the body. Stagnant liver qi, resulting from poor liver function, is associated with PMS and menopausal symptoms, hypertension, and gastrointestinal discomfort, as well as mood-related disorders such as depression, extreme anger and irritability, and severe mood swings." (Source: Herb Allure (HART) Master Reference)