Thanks for keeping us informed, since others may experience these same symptoms. So, idgIT, you feel much better having taken the 2 Centrums? //

Yes, there is such a thing as taking TOO MUCH of any certain minerals, vitamins, and irons. It's been advised for men 'being cautious' of iron toxicity. Not to mention the FDA is really watching the Vitamin/Supplement/ Herbals,-All Natural Companies,....perhaps you know by now, they have made DMSA very hard to find. Now, I get it from Amazon.com.
There are a few different combination of things that have helped others. Apple Pectin being another, modified citrus pectin, and always I find **ALGIN** (non-toxic) encourages normal elimation/absorbs Heavy Metal Ions. I know of others that take the ALGIN, and it's always a winner here and in other countries.

As I was Medically informed, "We all know our own bodies, and what helps or harms." So just beware. Maybe do your own research on possibility of 'mineral toxicity', 'mercury toxicity', etc.
ONCE again, you are here on Russ' page, be sure to read all the various testimonies above the Amalgam/Mercury Detox page.
Take care. Thanks for stopping by. As always, "What works for one, may not work for someone else."
Hope your legs are feeling better as well.