Thanks, I recently read, towards the ends of Cutler's book, that this is one side effect of ALA. I have been on it for three months and most of this time I have been taking it in doses of 100mm. I seem to tolerate it well. I do it every three hours now with 100mg of DMSA. I think that maybe I need to drink more water. Also, I am thinking of adding Probiotics back to my supplement schedule.