I take 500mg vit c, magnesium pills, 200iu vitamin e, 200% RDA B12, occasional selenium, and 2 alginate a day and I definitely find they help me. I'm not sure about the vitamin c, but the others certainly do. If I start missing dosages, I really start to suffer with pins and needles and other neurological problems from the mercury. I wouldnt take the high dosages of vitamins, though, on my belief that there is too much of a good thing.