The DMPS without ALA might not do that much good. I agree that to start with you should choose a low dose of DMPS alone without DMSA to see how you tolerate it. Perhaps you should start with just 25 mg the first round, just in case you get a very bad reaction to it. Perhaps if you tolerate the DMPS well and get the dosage up to 100mg after 4 or 5 rounds, then you should add ALA along with it? Initially the DMPS will get plenty of mercury out of the kidneys, but after that the ALA will be necessary to mobilize the mercury from the brain and nervous system, and to help remove it from the liver and thyroid.