DMSA is a very aggessive way to detox. I checked into it, but realized that it would be too much for me. As Carla said, you need to be taking a lot of magnesium and zinc because DMSA binds to those as well and removes them from your body.

It sounds like that could be a big part of your problem because low levels of magnesium can cause MANY problems with depression being one of them. I would suggest that you lay off the DMSA for a while and rebuild your good mineral stores. Then when you are feeling better, you might want to try some less dangerous chelation methods such as sodium alginate, selenium or even cilantro.