"I don't know how you guys can tolerate doses so high"

I started chelating with DMSA plus ALA in February. I started with 25 mg ALA + 25 mg DMSA. After a few weeks I went to 50 mg ALA plus 25 mg DMSA. My next step was to go to 50 mg ALA plus 50 mg DMSA. After that came 100 mg ALA plus 50 mg DMSA, then 150 mg ALA plus 50 mg DMSA, then my most recent round with 150 mg ALA, 62 mg DMSA plus cilantro the first two days. When the symptoms got weaker, I knew I was ready to try a higher dosage the next round. The worst that happens if the increase is too much and the symptoms are too great is that you stop the round, then the next round go back to the previous dosage. If you don't push the dosages higher, you won't make much progress. The target maximum dosage for DMSA is between 10 mg/kg/day and 30 mg/kg/day. For a 175 pound person, that means 100 to 300 mg per dose DMSA. Imo 300 mg per dose is too high, and I doubt I would go over 150 mg per dose. I do want to get to 100 mg per dose of DMSA pretty soon. I might stay at 100 mg DMSA dosage for a long time. How much ALA to use with that? Perhaps 200 mg? I doubt more than 300 mg.

"Right now i'm doing 6.25mgs of DMSA every four hours and im eating cilantro along with it. So far im ok, if it was just DMSA on it's own i couldn't do it. Cilantro seems to do something positive."

I did notice some positive effects of the cilantro this round. I ate plenty of fresh cilantro, around 20 grams (3/4 of an ounce) in two days. If you are afraid of adding ALA, then you could try raising the DMSA dosage to 12 and half mg next time, and increase the cilantro. Ultimately you should add ALA as well, but imo you shouldn't add any ALA until your DMSA dosage is at least 25 mg. Then you could start with 12 and half mg of ALA.

Last edited by JK98; 07/09/09 10:55 PM.