Linda, you might do better on 25 mg ALA +25 mg DMSA. I noticed that when I took ALA alone, my symptoms were much worse than with ALA plus DMSA. The DMSA seems to have a calming effect on symptoms. Taking just DMSA for the last few doses of a round also seems to prevent symptoms after the round ends.

I have been trying to increase the ALA dosage before increasing the DMSA dosage since DMSA is expensive, and ALA is so much cheaper, however when I notice stronger symptoms from the ALA it seems to mean that I need to increase the DMSA. Andy Cutler advises staying between a 1 to 2 to 2 to 1 ratio of DMSA to ALA.