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Joined: Dec 1999
Posts: 30,867
Master Elite Member
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400 IU of vitamin E is a very large dose. Vitamin E is a potent anticoagulant and large doses must be used with care. When I used to take vitamin E 400 IU years ago, I had nosebleeds. I now either take no vitamin E supplementation, or perhaps around 100 IU a day or so that is in a multivitamin. If you feel you don't get enough vitamin E in your diet, then perhaps take 100 IU a day. The latest research (and some publicly discounted early research) shows information related to the formerly-believed dangers of vitamin E to be untrue, although it has been believed to be true by the public and by many doctors for many years due to mainstream disinformation. Here is a link to some of it: Vitamin EHistorically, experts theorized that vitamin E would increase the effects of warfarin (Coumadin) by causing a deficiency of vitamin K—a fat-soluble vitamin responsible for blood clotting. However, in a recent double-blind clinical trial of 21 patients on chronic warfarin therapy, no significant effect on prothrombin times (a test that measures the clotting time of blood) was observed when 800-1200mg of vitamin E per day was given. Researchers concluded that "it appears that vitamin E can safely be given to patients who require chronic warfarin therapy.“8,25,26Vitamin E is a powerful brain antioxidant and I have been taking 3 to 5 per day—that's 1200IU to 2000IU per day—for years. I consider it a fundamental requirement for mercury toxic persons. --- 8 Ford-Martin, P. "Vitamin E.“ Gale Encyclopedia of Alternative Medicine.<http://www.findarticles.com/cf_dls/g2603/0007/2603000729/p1/article.jhtml>. Accessed April 2004.25 Swain, R.A. & Kaplan-Machlis, B. "Therapeutic uses of vitamin E in prevention of atherosclerosis.“ Alternative Medicine Review; 1999, 4(6):414-423.26 Kim, J.M. & White, R.H. "Effect of vitamin E on the anticoagulant response to warfarin.“ American Journal of Cardiology; 1996, 77(7):545-546.
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