I did a few doses last year with ALA only, and I couldn't continue. I think I did 5 or 6 rounds with 50 mg ALA, then crashed badly. A few months later I tried 25 mg ALA but couldn't even handle that. This year I started with 25 mg of each, then went to 25 mg DMSA 50 ALA, then to 50 mg of each. Perhaps it is the DMSA, or all the mineral supplementation I have taken that is allowing me to continue to chelate? I am getting strong symptoms on chelation, although they aren't intolerable as I experienced last year. Perhaps the high dosage(around 15 mg a day!) iodine that I took for a month also helped greatly? I stopped the iodine when I felt a slight bit of pain in my throid(
it wasn't bad, but I though that I might be overstimulating my thyroid). I think my temperature is much closer to normal these days(it was too low for a while).