4 days on and 4 days off sounds good. You can extend it if you want to try longer rounds at the same dose.

25 mg is a reasonable dose. I found I was fine on that with DMSA. 50 mg was a bit much for me in hindsight. And once I used to do that for one week on and one week off. And seriously, by about the 4th day I was feeling REALLY revolting. Sometimes I had to stop the round earlier than a week. But I never got the pscyho symptoms I got from other protocols - so to me this proved Andy's method because I was one of those very sensitive and poisoned people.

Thankfully Andy has made his protocol more flexible in dose and length of rounds for those more poisoned/compromised. So people are using much lower doses and for shorter time periods to match their needs/tolerance. Some may only be able to chelate on weekends if they have a busy schedule the rest of the week.