Hi Stuart,

You might find it easier if you take DMSA and ALA at the sametime (every 3 hours). Rather than taking one every 3 and the other every 4. Since DMSA can be taken every 3 hours like ALA, it would make it easier also and may help with symptoms. Both are meant to be taken together at the sametime - not separated. This maybe causing some issues.

What dose are you on again? You maybe taking too high a dose and this maybe why you are finding that you limit is about 12 hours before it become intolerable?

What symptoms is it causing out of curiosity? Because i had similar happen to me, even on DMSA alone and often could only chelate for a day sometimes and had to stop. I do not believe this is ideal, but I did not know what else to do as nothing else was tolerated either. This was usually when I was very toxic - both with mercury and yeast at the sametime. So this is why it's often essential to treat candida so you can deal better with the toxic mercury and the chelation itself.

Do you find you get after effects once you stop the round? If so, how bad are they? If not - you may get away with this, but certainly it's not recommended by Cutler. Ideally you want to do at least 2 - 3 days. But if your symptoms are intolerable, and you are on a very small dose - then it's very difficult to know what to suggest at this point.

I would definitely take DMSA together with ALA every 3 hours and reduce the dose if necessary. Are you taking the recommended supplements? As that apparently can help and maybe required moreso in your situation. Are you on any specific diet that may also help with symptoms? As toxins are more easily handled by a gut and liver that is not dealing with a high yeast situation. Otherwise you can get backfire effects far more easily and the body is less able to handle and keep up with the chelation. I found treating yeast made chelation FAR more manageable.

It will be doing something yes, but one hopes that the risks will not outweigh the benefits in this situation.

Have you thought of doing DMSA alone and seeing if the same thing happens? If not, I'd try doing that and judge the effects. You may require more DMSA alone and/or lower doses of either/both chelators.

You could also try ALA alone and see - as DMSA maybe causing a problem. it's very hard to say what exactly is going on here. Most likely it's just a high mercury situation and you are just simply very very toxic, which is why very small doses maybe required to handle this more and/or going back to DMSA alone for awhile perhaps and trying ALA later or as I said, if you suspect DMSA maybe an issue, trying ALA alone.

There are various things you could experiment with to see if you can find out why this is occuring. Certainly diet and supplements are necessary to support this process and should never be ignored.