Hi Bex, According to my Mri (brain) I apparently have a very compromised bbb. This would be the reason for my spine spasms and brain effects. I used to think the reason for my apparent improvement late at night and wee hrs in the AM was adrenals only but I really think it's also the fact of less electrical interference in those hours. My brain is a basic battery with all the metal. Wish I knew how to repair the bbb effectively...