I've tried this product which was taking away from me as i was returning to the UK from a holiday! I have to admit it made a difference. I've tried a lot of chelating agents like ALA and DMSA and i could really tolerate HMD(i couldnt the others). It makes you feel slightly drunk and it does mobilise a lot of metals. I would recommend you take Algin with it. To answer your question though it does work. It may not be the whole answer but it certainly helped me somewhat. I just now have to buy another bottle(it aint cheap either)