I mentioned before that I got bad symptoms from methylcobalamin and many other supplements that had the word methyl in it. The reason I believe is that they donated their methyl group to mercury in my system, resulting in methylmercury which is a very toxic form of mercury that can cross the blood-brain barrier. I would get horrendous insomnia from methylcobalamin yet could take other forms of b-12 without a symptom.

I searched up MSM real quick and got this
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Interestingly, MSM, like folate, is a methyl donor.


So if it is making you feel worse, it could be because it is methylating mercury in your system which could increase mercury levels in the brain. Not something I would risk, especially knowing how I reacted to other methyl containing supplements.

Many things have detoxifying capabilities. Brassicas (Cabbage, Broccoli, etc..), Garlic, Onions, Turmeric, etc all can help your body detoxify, and include a variety of natural sulfur compounds.