Perhaps you could take up to 3 or 4 B25s a day, or cut the B50s in half if you can't find B25 pills. Taking 4 B50s a day would be a stress on your body, especially if you don't drink huge amounts of water. Perhaps a mome conservative idea might be to take a B25 twice a day. For a maintenance dosage, up to 50 mg a day of zinc could be taken. For short periods of time during severe illness you could take up to 100 mg a day of zinc. A gram of vitamin C(Ester C is best. It also is a source of calcium and is buffered) 2 or 3 times a day would be a good idea.