Methodological materialism is probably a very good definition/description of most science as we know it today. It's probably all we'll ever have. I guess there are areas of physics that attempt to move beyond that. Not sure what else, I don't really include metaphysics in the realm of always completely persuasive 'science' myself, being so dependent on the view of the individual observer. It may be applicable to a degree but certainly for not everyone everywhere at all times, like gravity or inertia. Psychology/psychiatry enters the realm of metaphysics somewhat and makes many mistakes as a result, for instance, because no 2 single people on this planet are exactly the same. and assuming anyone has all the answers all the time has got to be the biggest mistake ever.

The problem with relying on something like methodological materialism as a final answer is real apparent. For instance, science can explain how our bodies work, somewhat, and to a large degree they have a lot of info. But that's assuming they have not missed anything ever in numerous autopsies and dissections... chances are actually quite good they have missed things, things so small no one has ever noticed them... and then you cannot overlook the fact that science cannot explain why your heart beats or how, only that it does and through what observable means... if science had the answer to how and why it could raise the dead without a problem.

And then there is the thought realm... the how and why and what... which is far beyond the realm of methodological materialism, but without which man would have never achieved a single thing. Man may have access to all the matter on this earth but without the idea to spark the process, he never would mold any of it to any good use. Before there was a toaster, there was an idea. The idea is actually more important than the toaster in that sense. the toaster is the result of the idea, not a cause and effect within itself. The thought is the cause.

So, essentially, methodological materialism or philosophical materialism, of which evolution is a branch of, starts off only where it can observe itself as matter, leaving all the rest, the hows and why behind, not because it wants to but because it has to.

Science, as we know it, is not complete. Most well educated scientists are also very aware of that far as I know.

The bible says God created man in his image. Science as we know it, only includes measurable observable matter. Not included in science are things like life itself, where, how why... and things like thoughts, which many seem to feel are more powerful than we give them credit for. If you go around thinking bad thoughts all the time, your life probably isn;t going to be real great, most people know that. If you exude a cheerful happy attitude, people will enjoy your company more. And then there is a mysterious thing we know as charisma, magnetism, some people have it, some don't. What is it? All of these little things we know as facts but science will never explain them as observable material facts or items. Because they are not matter. Imagine God then, as we are in his image, but how much more bigger more powerful his thoughts are than our own, his charisma, his life. But imagine is all we can really do, because none of us really is God to truly compare our experiences and abilities to his.

Materialistic science completely fails to answer the foremost question... what is life? and it always will, because life itself, the thing that makes the heart beat, the force that raises the dead, is outside the realm of matter. We only know some things are alive and then they are dead when life is gone out of them. We have very few answers really. Life itself, the force of life... we know it is... we do not know what it is.