Yes, I agree that it all depends on what works for you. I never had problems going on and off ALA (20-25 mg every 3 hours), so I stop for nights and continue in the mornings. My only problem is that if I stay too long, non-stop on ALA (the every 3 hour schedule), I may get a die-off that gains momentum on its own. It has to be added that bad things started happening (various toxins started accumulating), unless done with additions as I suggested above. ALA alone was no good for me.