I don't know enough about time-release ALA to know whether it would work that way. I know Andy talks about the normal ALA and there doesn't seem to be anyway around it, other than either doing it every 3 hours, or going off his protocol and taking risks.

I think only you can answer that. I would be taking risks with your health by suggesting otherwise. I think even if you asked this on the frequent dose forum where all they do is discuss the Cutler protocol, you would probably be told that there is no other way, you either comply with the protocol and put up with the broken sleep, or you do your own way and risk adverse outcomes.

There just isn't enough info on time release to know if you can get away with it and that it will just continue to release slow ALA into your system over hours.

It is really up to you if you want to try that. I personally would not I don't think. I'd be too scared. I'd chelate on weekends and do the every 3 hours. You can stretch it to every 4 I guess, which is still taking a risk, but it is better than missing the nightly doses altogether. Even every 4 hours is a bit too long for ALA.