Silymarin, a bioflavonoid found in Milk Thistle (Silybum marianum) extract, increases synthesis of hepatic GSH by as much as 35%

Vitamin B1 (Thiamine) and Vitamin B6 (pyridoxine) are essential in the synthesis of sulfur-ontaining amino acids, and must be included in the mercury detoxification regimen. Mercury causes rapid turnover of thiamine in the brain by converting it to thiochrome. Interestingly, the symptoms of Vitamin B1 deficiency and mercury toxicity are almost indistinguishable.

Selenium is an essential trace element, which is vital to the activation of GSH- containing, liver detoxification enzymes and also to the antioxidant enzyme, Glutathione peroxidase, important in neutralizing free peroxide radicals and oxidized lipids. Tolerance of selenium may be limited by its binding to, redistribution and precipitation of mercury in the tissues, which may induce nausea, digestive disturbances, vertigo, etc. For those who do not tolerate selenium, use of Vitamin E (Tocopherols and Tocotrienols) to counteract mercury-induced, tissue lipid peroxidation is indicated. Vitamin E works with selenium to neutralize mercury.

Zinc is important in the production of Metallothionein, present in L-Cysteine, which detoxifies mercury.

Molybdenum decreases accumulation of mercury in the kidneys by increasing urinary excretion.

Chronic exposure to mercury vapor depresses adrenal gland stores of ascorbic acid (Vitamin C), thus diminishing the bodys response to oxidative stress and infections. Supplemental Vitamin C, in both the water- and lipid-soluble forms, is critical to adequate, systemic mercury detoxification.

Garlic extract, containing high amounts of sulfur allyl compounds, particularly allicin, is helpful in the gradual removal of low levels of mercury from the body