Selenium is an essential trace element, which is vital to the activation of GSH- containing, liver detoxification enzymes and also to the antioxidant enzyme, Glutathione peroxidase, important in neutralizing free peroxide radicals and oxidized lipids. Tolerance of selenium may be limited by its binding to, redistribution and precipitation of mercury in the tissues, which may induce nausea, digestive disturbances, vertigo, etc. For those who do not tolerate selenium, use of Vitamin E (Tocopherols and Tocotrienols) to counteract mercury-induced, tissue lipid peroxidation is indicated. Vitamin E works with selenium to neutralize mercury.