EDTA has virtually no affect on chelating Hg. However, if taken in combination with DMPS has the affect of helping the Hg out of the blood system and stopping it from being reabsorbed. So, DMPS grabs the Hg and wrenches it away from being bound to proteins in you major organs and delivers it into the blood system. Normally some would be filtered out through the kidneys and bile duct and some would be re-adsorbed, but with the EDTA present it binds to the Hg and stops allot of this re-absorption resulting in higher levels of excretion. This is how it was explained to me by my Doc. And it did seem to enhance the results. From my test results it seemed I was always absorbing the arsenic present in NY water. Either that or my girlfriend was trying to do away with me, which, thinking about it, is not so far fetched considering what a horrible person I used to be. I’ve since had a complete personality change and she’s fallen in love with me all over again at least twice since starting this whole Hg thing.