Hi Dawn
I've been using the natural progesterone cream since May of this year.It had immediate calming effect,is beautiful on my skin.I'd say It took a good 3 months to kick in for pmt symptoms
to go almost completely,did not get symptoms this month.
It is worth the wait.I use one called "Naturone"it's a Beautiful cream.
I'd be interesting to see what you think of it.Keep us posted.