I only took one injection, and I know it's supposed to be a series, but I felt like it might have made my fatigue worse. Not sure, as my fatigue fluctuates between bad and worse all the time, but that was my experience. I've also tried liquid B vitamins as well as yeast-free tablets and Stress tabs, all of which DEFINITELY made me feel more tired...is that even possible?! <img src="/ubbthreads/images/graemlins/crutches.gif" alt="" />