hi jinx : I started using low dose dmsa and ala 12.5 mg each this is my first round ,I feel like I have a mild hangover but my back pain is going away I am going to try low dose for a longer period instead of higher dose for a shorter period so far low dose isn't too bad , just remeber that you are not alone in your recovery ,and one day hopefully soon this will be just another bad memory for us , so hang in there