I just looked up oregon graperoot extract. Interesting stuff, especially for those who are constipated. It is very different than grapefruit seed extract.

http://health.howstuffworks.com/medical-uses-for-oregon-grape-ga.htm

I never used oregon grape root extract. Olive leaf extract and grapefruit seed has helped me very much with a candida infection. candida problem. You might want to consider adding it to your regimen. Imo these herbs probably have a synergistic effect when taken together.