I have done my own self supplementation with loads of herbs and amino acids and vitamins as well. I also would like to know if this can cause a biochemical change and what can we do to sort it out or find out exactly whats changed(expecially if its long term or permanent).

I have taken all of those you mentioned though not all at the same time execpt in specific formula's.

Im currently taking passiflora and st johns wort.