if you are on testosterone replacement therapy , then taking dhea is probably not be a good idea ,because if taken alone dhea will raise testosterone levels on it own , but if taken with t supplimentation who knows what problem you may encounter ,I would use one or the other ,with that said, then with either one that you choose ,you should be taking an anti estrogen suppliment as both t suplimentation and dhea increases estrogen and dht very easily ,50 mg of zinc daily is a very good and inexpensive anti-estrogen and saw palmetto is very good at keeping dht in check ,high dht levels can cause prostate problems along with hair loss