I have two merc amalgams in my mouth and the fillings are fairly surface level (not deep in the tooth acording to my xrays). My doc has me chelating using Detoxamin 2 X week while I get ready for amalgam removal. She said that it is important to open up a detox pathway for your body to start removing the merc and other heavy metals ( I also have cadmium, nickel, lead). So far I feel fine with this level of chelation. My detox symptoms are mild.