Be careful about taking too much vitamin E. Vitamin E is a poweful anticoagulant. Especially if you are taking a large dosage of vitamin c(a more mild anticoagulant that still has a strong effect at very high doses). If you a taking over a gram a day of vitamin c then you might want to keep your vitamin E supplementation at 200 IU or less or perhaps even 100 IU or less unless a doctor specifically tells you to take a higher dosage. When I took over 400 IU a day of vitamin E and also took plenty of vitamin c I had a problem with nose bleeds. Decreasing the vitamin E to around 100 IU a day stopped the nose bleeds. Zinc is very non toxic. Some people take 30-50 mg a day , while others take more than that for short periods of time during illness. Vitamin C is very non toxic. Some say that a few grams a day spread out throught the day should be taken during illness. A more conservative approach would be to take 500 mg or a gram a day. Ester C is the best form to take. Around 500mg of magnesium a day would be a good dosage. If your diet is not high in calcium then consider also taking a gram a day of calcium. Calcium citrate or calcium ascorbate would be a good form to take.