I'm more and more convinced that Cutler's protocol is the way to go. You have a lot of people on it in a visible way: the Yahoo groups "adult metal chelation" and "frequent dose chelation."

So you can see what's going on pretty well. Most people seem to do well on the low dose, continuous protocol.

Conversely, the huge dose, randomly timed methods appear to cause substantial problems. So theoretically Cutler's protocol makes sense, and in reality it appears to work as well.