Hi,
I jumped from taking 50mg of ALA to 250mg. I could not tolerate DMSA as I got liver pains. Cutler makes it clear that DMSA is bad on the liver while ALA is good on the liver. Therefore, you should see whatever works for you. I would personally experiment with one chelator at a time to see how high you can go on it, to see if you can even tolerate it. If you feel bad mentally or emotionally on the dose, I would stop the round and wait to start at the lower dose.

Best