HI Claythrow, DMSA is not actually for your organs/brain, it is to chelate/reduce the mercury in your blood and tissue. It may indeed, to a certain extent, chelate "some" organ mercury, but does NOT chelate mercury from the brain to any clinical degree.

alpha lipoic acid chelates organ and brain mercury (everything basically), which is why it is wise to use it much later in the programme once you have reduced blood levels first. DMSA is good for doing that.

Some people decide to skip DMSA and go straight to ALA, but they are advised to wait for about 3 months post amalgam removal (or any mercury exposure) to allow the blood levels to reduce first naturally. Then they can use ALA on it's own if they wish from then on.

MOst do DMSA first for about 3 months or so and then add ALA after that. EVen if you are past 3 months post amalgam removal and can use ALA, but haven't yet tried DMSA, you may want to give DMSA a go first regardless on its own and see if you notice anything, because even then at that stage, it may still remove more mercury from those areas and you may want to do that for a while anyway. Some do this as an extra cautionary measure. it's not absolutely necessary, but it is a good move.

Those who cannot tolerate DMSA don't have much choice, and simply go straight to ALA after the 3 months of doing nothing. According to Andy, ALA is essential anyway. He feels DMSA is more optional. Though I know people who have gotten well by DMSA alone, so I think it's much stronger than its being made out to be and I always feel it's worth a try before doing anything else.

25 mg - 50 mg, is a typical starting dose, though some are so toxic, they have been known to have to use far lower doses, even 6 mg - 12.5 mg. I found 25 mg to work for me in the beginning and later 50 mg was ok. Some start at 50 mg and can move up to 100 mg.

Whatever works for the person. No need to tolerate side effects that overwhelm the person, because if you get enough on 6 mg, you are stilll chelating mercury at that level at at a dose your body can tolerate and keep up with.