Yes I had similar problems when on DMSA. The DMSA still helped though once you were past taking it! I have just had an appointment with Jacques Imbeau who is considered to be pretty on to it with detox etc and he has suggested that we get my gut sorted first and then relook at detox at that stage. On to a candida free diet and taking homeopathic and herbal stuff to help as well. He calls it weed seed and feed. We spend approx 4 weeks killing them(weed) then go on to taking good bacteria probiotics etc (seed) and then nutrients etc (feed). Then remove my amalgams and then detox/chelate.