Thanks a lot for this detailed explanation Bex! All your posts are really helpful. So basically the point of increasing the dose is to chelate more mercury and faster. So if I chelate with 25mg of DMSA and ALA without increasing it, then I am looking at about 2 years of frequent dose chelation, but if I get up to a 100mg for each, then I would be in the 6 months range. And whether I will be forced to go, based on how I feel, with the low dose or high dose, if after a few more rounds post frequent dose chelation I have no side effects and not feeling any different, then I am done or cleaned or cured right? By the way my first DMSA round begins in 20 minutes, I set my cell phone to alarm every four hours. <img src="/ubbthreads/images/graemlins/shocked.gif" alt="" />