I can't say for sure as my naturapath doctor,gave me the info about this,it has done some great things for alot of people,i have a bottle of it,i tried it at the recommended dose for about a week,and got alot of detox symptoms,so she told me to give it a break as i am probably moving things too fast,so i have no real proof other than a few of her patients that can sy for sure they benefitted from taking it.